Jenis ini terjadi jika kandungan asam tubuh terlalu rendah, sehingga tubuh lebih banyak mengandung basa. Kondisi ini dapat disebabkan karena muntah yang berlebihan dan berkepanjangan hingga kehilangan elektrolit (terutama klorida dan kalium), konsumsi obat tertentu yang berlebihan (diuretik, antasida, atau obat pencahar), penyakit kelenjar adrenal, konsumsi bikarbonat, serta kecanduan alkohol.
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Keseimbangan cairan
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